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"Madhouse" is a single by thrash metal band Anthrax, from the album, Spreading the Disease. The song is an up-tempo song with hard riffs and contains one of the strongest thrash tempos Anthrax has created in their early time. The song has become a staple of live concerts, and has also appeared on Anthrax's "best of" album, Anthrology: No Hit Wonders (1985-1991). It is included in the 2002 video game Grand Theft Auto: Vice City, on the fictional radio station V-Rock. .

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